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PRODUCTS |
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TECHNICAL FILE |
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COMPOSITION |
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Cyproterone Acetate 2.00 mg + Ethynil estradiol 0.035 mg. |
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THERAPEUTIC ACTION |
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The drug substance cyproterone acetate contained in Genoderm blocks the effect of endogenously produced and exogenously administered androgens at the target organs through competitive inhibition.
Apart from the described anti-androgen effect, the cyproterone acetate has a progestational effect. Ethynil estradiol in the combination inhibits ovulation and alters the cervical mucus and the endometrium, rendering them unfavourable for sperm penetration and fertilized egg nidation, respectively. |
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INDICATIONS |
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Androgen-dependent acne, especially those forms presenting with seborrhoea, inflammation or nodule formation (papulopustular acne, nodulocystic acne), androgen-dependent allopecia and mild forms of hirsutism. Oral contraception in women requiring anti-androgen therapy. |
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DOSAGE AND ADMINISTRATION |
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Genoderm should be administered once daily for 21 days. Resume therapy with a new pack after a 7-day break. Genoderm is started on the first day of the cycle (the first day of the menstrual bleeding).
Warnings, adverse reactions, interactions and contraindications.
See contraceptives (General overview). |
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HOW SUPPLIED |
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Genoderm is available in packs containing 21 tablets. |
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